2. Signaling Pathways
  3. Membrane Transporter/Ion Channel
  4. Na+/Ca2+ Exchanger
  5. Na+/Ca2+ Exchanger Activator

Na+/Ca2+ Exchanger Activator

Na+/Ca2+ Exchanger Activators (2):

Cat. No. Product Name Effect Purity
  • HY-B1193
    Terfenadine
    		Activator 99.91%
    Terfenadine ((±)-Terfenadine) is a potent open-channel blocker of hERG with an IC50 of 204 nM. Terfenadine, an H1 histamine receptor antagonist, acts as a potent apoptosis inducer in melanoma cells through modulation of Ca2+ homeostasis. Terfenadine induces ROS-dependent apoptosis, simultaneously activates Caspase-4, -2, -9.
  • HY-B1193R
    Terfenadine (Standard)
    		Activator
    Terfenadine (Standard) is the analytical standard of Terfenadine. This product is intended for research and analytical applications. Terfenadine ((±)-Terfenadine) is a potent open-channel blocker of hERG with an IC50 of 204 nM. Terfenadine, an H1 histamine receptor antagonist, acts as a potent apoptosis inducer in melanoma cells through modulation of Ca2+ homeostasis. Terfenadine induces ROS-dependent apoptosis, simultaneously activates Caspase-4, -2, -9.